Glucose-stimulated Insulin Biosynthesis Depends on Insulin-stimulated Insulin Gene Transcription
نویسندگان
چکیده
منابع مشابه
Insulin enhances glucose-stimulated insulin secretion in healthy humans.
Islet beta-cells express both insulin receptors and insulin-signaling proteins. Recent evidence from rodents in vivo and from islets isolated from rodents or humans suggests that the insulin signaling pathway is physiologically important for glucose sensing. We evaluated whether insulin regulates beta-cell function in healthy humans in vivo. Glucose-induced insulin secretion was assessed in hea...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2000
ISSN: 0021-9258
DOI: 10.1074/jbc.m005216200